27 results
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Spherocytes • Treatment ... Mycoplasma, HIV, EBV ... transient hemolysis • Treatment ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Antisynthetase Syndrome (ASS ... Body Myositis (IBM ... Idiopathic #Myopathy #Comparison ... Managment #algorithm #Rheumatology ... #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - PNH - APLS ... mountain spotted fever ... Vasculopathy #Purpura #Differential ... #rheumatology #
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Rare inflammatory disorder ... : High spiking fever ... Systemic AOSD: high fever ... , CRP, AST+ALT, ... Disease #AOSD #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... neoplasms) • Screen also ... glucocorticoid treatment ... #Algorithm #Differential ... #diagnosis #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... fraction < 20% Differential ... Coxsackie, CMV, EBV ... diagnosis #management #treatment ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... not required in all ... When do you do a BM ... #Differential # ... Causes #Workup #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential ... B symptoms not as ... Responsive to Treatment ... pathophysiology #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... - Pel-Ebstein fever ... body, but can also ... #NonHodgkins #comparison ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Mycoplasma, EBV ... younger pts) Differential ... Such As: • IgM ... Symptoms: High fevers ... hemolytic #anemia #hematology