27 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
(TLS) and Treatment ... Abnormalities of TLS ... Laboratory TLS ... #TLS #diagnosis ... #management #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... leukapheresis - TLS ... Low calcium • Treatment ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Triggers: ATRA treatment ... #APML #diagnosis ... #management #hematology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... but can also spontaneously ... and AML) and solid ... #TLS #oncology ... #management #UricAcid
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... of the above Treatment ... of Clinical TLS ... MatthewHoMD #TLS ... #diagnosis #management
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... to be present Treatment ... Antiphospholipid #Syndrome ... #APS #diagnosis ... #management #anticoagulation
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... Summary Diagnostic ... transformation into AML ... #Management #Summary ... #treatment #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... Generalized fatigue - ALS ... myasthenia Diagnosis ... Myasthenia #Gravis #diagnosis ... #management #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... permeability Diagnosis ... (for secondary APS ... CNS #neurology #rheumatology ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as ... tests ↑ AST ↑ ALT ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology