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hematology management monoclonal gammopathy chronic cll leukemia lymphocytic multiple neurology pathophysiology sclerosis significance als amyotrophic avascularnecrosis complications cushings differential endocrinology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... - Differential Diagnosis ... Ig deposition disease ... #hematology #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
1 or more: • Clonal ... of MM), light chain ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
constitutional symptoms ... type) < 3 g/dL • Clonal ... proliferative disorder • Clonal ... Significance #hematology #diagnosis ... #oncology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Management Summary Clinical ... Signs: • hyperCalcemia ... demineralization) • Renal disease ... 48% (light chain ... #Management #oncology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Hyperreflexia, Clonus ... Signs and symptoms ... patients with clinically ... stimulation Clinical
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... cytometry → >500/uL clonal ... immunophenotype Clinical ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Significance (MGUS ... treatment of infective symptoms ... Ig deposition disease ... rituximab (in clinical ... Complications #diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... Presentation: - Disease ... course of the disease ... Jaw Jerk reflex, Clonus ... fasciculations Common Symptoms
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
Pathogenesis and clinical ... and destroying thin ... pathophysiology #signs ... #symptoms #diagnosis ... #otology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... #workup #oncology
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