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diagnosis hematology management leukemia chronic comparison hodgkins lymphoma algorithm anaesthetic anesthesia anesthesiology bronchoscopy cancer checklist classification cold differential gammopathy hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... • Age: 60-80 Clonal ... CLL Symptoms: • ... transformation of the CLL ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... Orange or Hep C Clinical ... with no early symptoms ... Leukemia #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... cytometry → >500/uL clonal ... immunophenotype Clinical ... Transformation to large cell ... uw_IMresidency #CLL
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
typically of B-cell ... Reed Sternberg cell ... type (B cell, T ... body, but can also ... , ALL) • Solid
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Management Summary Clinical ... marrow plasma cells ... cell in bone marrow ... if FLC value is also ... Diagnosis #Management #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... involve one, two, or all ... Workup: • Complete ... diagnosis #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Hodgkin Lymphoma - Clinical ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... classification #hematology #oncology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
life Causes and clinical ... and duration of symptoms ... histology - Mast cell ... infiltration (lymphocytes ... doi: 10.1111/all
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia Signs of severe toxicity: • Sudden alteration in
without tonic-clonic ... tachyarrhythmias may all ... infusion pumps). ❷ Call ... inform immediate clinical ... of problem. ❸ Call
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
When to look for clonal ... ) - Clinical symptoms ... Cytopenia, Other cell ... BM biopsy (Mast cells ... Signs #Hematology #Workup
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