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hematology management algorithm anemia lymphocytic myelodysplastic treatment allergy cancer classification cnl comparison disorders eosinophilia erythematosus hemeonc hodgkins infections infectiousdiseases lupus
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... • Age: 60-80 Clonal ... ) CLL Symptoms: ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... aplasia • ITP ... #Leukemia #diagnosis ... #workup #oncology
Chronic Neutrophilic Leukemia (CNL) • Signaling Pathway • WHO Dx Critera • Risk Stratification • Treatment
Chronic Neutrophilic ... Leukemia (CNL) ... Zhuoer Xie, MD ... #Leukemia #diagnosis ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... cytometry → >500/uL clonal ... Lauren Banaszak, MD ... #Leukemia #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... transformation to acute leukemia ... Allogeneic stem cell ... Myelodysplastic #Syndrome #MDS ... treatment #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Script Signs and symptoms ... Consider stem cell ... Can progress to MDS ... or acute leukemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... Hypocellular/Hypoplastic MDS ... • Improve the symptoms ... #Anemia #oncology ... #hematology #diagnosis
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Eosinophilia - Differential ... Diagnosis Algorithm ... • Eosinophilic Leukemia ... • MPN/MDS w/ eosinophilia ... insufficiency, Chronic
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involved) • No leukemic ... involvement Differential ... Diagnosis of B-Symptoms ... NonHodgkins #comparison #oncology ... #diagnosis #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Causes • Anemia • Aplastic ... Marrow Failure • Chronic ... blood count with differential ... #hematology #oncology
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