16 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Leukemia (CLL) ... • Most common leukemia ... in adults • Disorder ... cytometry → >500/uL clonal ... #Leukemia #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Lymphadenopathy - Differential ... • Chronic Lymphocytic ... Lymphocytes) ... - Monoclonal Lymphocytes ... Causes #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... Leukemia): • Lymphocytes ... • Age: 60-80 Clonal ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... with no early symptoms ... lymphoproliferative disorders ... #workup #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential ... pattern of spread, B symptoms ... Treated Like Acute Leukemias ... Lymphoproliferative #Disorders
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
, monocytes, & lymphocytes ... Leukemoid reaction ... disorders: > 100,000 ... part automated differential ... Leukemoid Reaction
The hematopoietic tree and the resulting leukemias and lymphomas 
The hematopoietic tree refers to the hierarchical
the resulting leukemias ... self-renew and differentiate ... are malignant disorders ... abnormal growth of lymphocytes ... Acute leukemias
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- B symptoms ... involved) • No leukemic ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Episcleritis Signs and Symptoms ... development of skin symptoms ... certain types of leukemia ... #dermatology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Hematologic disorder ... constitutional symptoms ... type) < 3 g/dL • Clonal ... • Clonal bone ... hematology #diagnosis #oncology