15 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse Lymphadenopathy ... - Differential ... Lymphocytes) ... Lymphoma #Diffuse #Lymphadenopathy ... Causes #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... Leukemia): • Lymphocytes ... • Age: 60-80 Clonal ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Leukemia (CLL) ... cytometry → >500/uL clonal ... ) Asymptomatic lymphadenopathy ... Symptomatic massive lymphadenopathy ... #Leukemia #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... • Lymphadenopathy ... Exam/Signs: • Lymphadenopathy ... #workup #oncology
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
and Localized Lymphadenopathy ... - Differential ... • Neoplastic (Leukemia ... #LAD #Differential ... Causes #Hematology #Oncology
Differential Diagnosis for Generalized Lymphadenopathy

Viral
• HIV 
• EBV 
• CMV 
• HBV 
• Dengue 
• Rubella
Differential Diagnosis ... for Generalized Lymphadenopathy ... • Lymphoma • Leukemia ... #Differential # ... Causes #Algorithm #Oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... (NHL) ~60% - lymphadenopathy ... pattern of spread, B symptoms ... Treated Like Acute Leukemias ... Diagnosis #NonHodgkin #differential
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... malignancy: • Symptoms ... : B-symptoms, bruising ... immunosuppression • Exam: lymphadenopathy ... hematology #WBC #Leukemoid
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
involved) • No leukemic ... , lymphadenopathy ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
Bacterial Meningitis - Differential ... Adenovirus, • Lymphocytic ... Coltivirus Symptoms ... influenzae Symptoms ... suffusion • Lymphadenopathy