2566 results
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
crystals from joints ... high-resolution ultrasound ... warm, swollen joint ... sclerosis & cysts, joint ... Signs #Symptoms #Pathophysiology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Pathogenesis and Joint ... poly-articular joint ... Joint involvement ... space decr joint ... RheumatoidArthritis #RA #pathophysiology
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
together) • Joint ... closer to the joints ... ) • Joint Subluxations ... (Joint deformities ... Radiology #Clinical #Pathophysiology
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Inflammation of joints ... commonly large joints ... Oligoarthritis: Joint ... pain in a few joints ... ReactiveArthritis #pathophysiology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint ... 3) Number of Joints ... weight-bearing joints ... Number of Joints ... ): • Septic joint
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
and Degenerative joint ... Inflammatory Joint ... Swelling stimulates joint ... • Moving the joint ... JointPain #Diagnosis #pathophysiology
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
= definite RA Joint ... 2-10 large joints ... , +/- large joints ... points >10 joints ... least 1 small joint
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Stimulation of joint ... loading / use of joint ... Disruption of normal joint ... movement of the joint ... Osteoarthritis #OA #pathophysiology
Common Forms of Arthritis in the Hands

Acute Rheumatoid Arthritis 
Tender, painful, stiff joints in rheumatoid arthritis,
painful, stiff joints ... interphalangeal joints ... interphalangeal joints ... (Degenerative Joint ... Joint involvement
Phalanges - Hand Anatomy

Joints between phalanges are named interphalangeal meaning “between phalanges.” Because each finger has
Hand Anatomy Joints ... interphalangeal joints ... interphalangeal) joint ... interphalangeal) joint