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Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Red Blood Cell (RBC ... cell, Other RBC ... bodies, Howell-Jolly ... bodies #RBC
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... Associations • Howell Jolly ... Sickle cell, MDS #RBC
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... / Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Classification #Approach #Differential
Urine Microscopy and Casts - Image Atlas Key - Squamous Epithelial Casts - Transitional Epithelial Cells - Renal Tubular
- Monomorphic RBCs ... - Dysmorphic RBCs ... Granular Casts - WBC ... Cast - RBC Cast
The differential diagnosis for an elevated MCHC (mean corpuscular hemoglobin concentration) includes: Conditions with Abnormal RBCs: •
The differential ... with Abnormal RBCs ... : • Abnormal RBC ... Xerocytosis • RBC ... Elevated #MCHC #Differential
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Macrocytes, Normal RBCs ... Spherocytes, RBC ... ) - Abnormal RBCs ... Normocytic #Anemia #Differential
Algorithm and Differential Diagnosis of Macroscopic Hematuria Important Historical Elements: - Painless: suggests malignancy - Painful: suggests calculi/infection - Urinalysis:
Algorithm and Differential ... dysmorphic RBC’s, RBC ... /WBC casts, proteinuria ... #Macroscopic #Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... 2) External (RBC ... 3) Internal (RBC ... Smear ↑ abnormal RBCs ... #Hemolysis #Differential
Urinalysis Interpretation (UA) Bacteria, Leukocyte esterase, WBC, Nitrite, RBC, Epithelial cells, pH #Diagnosis #Urinalysis #Interpretation #Analysis
Leukocyte esterase, WBC ... , Nitrite, RBC,
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 Post-splenectomy blood smear demonstrating Howell-Jolly bodies and target cells. #Clinical #Pathology #BloodSmear #HowellJollyBodies #TargetCells #Splenectomy #Asplenic
demonstrating Howell-Jolly
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