125 results
Paget's Disease of Bone

 • Characterized by an ↑ rate of bone turnover with both excessive
by an ↑ rate of bone ... and formation of bone ... • Caused by ( ... more (polystotic) bones ... pelvis, and long bones
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... excessive bone ... MSK • Deformed bones ... Lytic lesions make bones ... of middle ear bones
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long bones ... BrighamChiefs #Bone ... differential #diagnosis #causes
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Skeletal: - Bone
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis Algorithm ... Granulomatous Disease ... Miscellaneous - Bone ... Hyperthyroid, Bony ... #causes #endocrinology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... - Bone symptoms
Hand X-Ray Anatomy and Interpretation Checklist
1. Soft tissues - Look carefully at the soft tissue over
tissue over all the bones ... Bones - All the ... bones of the hand ... in between the bones ... to the carpal bones
Main causes of diffuse parenchymal lung diseases.

#differential #algorithm #diagnosis #causes #DPLD #ILD #parenchymal #lung #diseases #pulmonary
Main causes of diffuse ... #differential #algorithm ... #diagnosis #causes ... #DPLD #ILD #parenchymal ... #lung #diseases
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Causes of Dizziness ... Differential Diagnosis Algorithm ... • Meniere's Disease ... Media • Temporal Bone ... #Causes
Osteomalacia & Osteoporosis in People with HIV
Osteomalacia:
 - Decreased bone matrix mineralization. In people with HIV
- Decreased bone ... (from multiple causes ... ) - Bone pain/ ... of underlying cause ... Osteoporosis: - Loss of bone