14 results
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... MSK • Deformed bones ... Lytic lesions make bones ... Nerve Palsies • Disordered ... of middle ear bones
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
of bone, joint, ... inflammation of the bones ... • Bone and joint ... Rule out other causes ... osteoarticular and skin disease
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Differential Diagnosis Algorithm ... Tumours - See Bone ... • Bone Marrow ... Disorder • Endocrinopathy ... #Orthopedics #Causes
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... mutations - BMPR2 (bone ... , thyroid disorders ... Hypertension #PHTN #Classification ... #Differential #Causes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Chronic diarrhea / IBD ... Pancreatitis - Hungry bones ... Magnesium #Table #Classification ... #Causes #Workup
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Differential Diagnosis Algorithm ... • Cushing's Disease ... Chemotherapy • Bone ... Celiac, IBD) • ... endocrinology #causes
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
particular affinity for bone ... areas include the bones ... pituitary gland • Bone ... ribs, and long bones ... Liver, Spleen, Bone
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... ) Classification ... anymore • Routine bone ... number of sites of disease ... lymphoma #diagnosis #classification
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
• Domestic and wild ... status NTM Cause ... Growers (Runyon Classification ... Growers (Runyon Classification ... ) - Bone Marrow
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Summary Group of disorders ... the extent of disease ... muscle wasting Bone ... -1 & IL-6 → AA Protein ... hypoadrenalism • Nausea