18 results
diagnosis differential orthopedics treatment dermatology hemophagocytic hlh jointpain lymphohistiocytosis pathophysiology rheumatology airway ascorbicacid atopic atopy casts cell chronic cico clinical
Paget's Disease of Bone • Characterized by an ↑ rate of bone turnover with both excessive
by an ↑ rate of bone ... • Caused by ( ... more (polystotic) bones ... pelvis, and long bones ... #management #treatment
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... formation MSK ... • Deformed bones ... Lytic lesions make bones ... of middle ear bones
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
Differential Diagnosis Algorithm ... Tumours - See Bone ... • Bone Marrow ... Fractures #Pathologic #MSK ... #Orthopedics #Causes
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... inflammation of the bones ... Rule out other causes ... osteoarticular and skin disease ... Rheumatology #diagnosis #management
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
Peripheral Vascular Disease ... fractured long bone ... • Dislocated Bone ... Vascular #JointPain #MSK ... #Orthopedics #Causes
Chronic Joint Pain - Differential Diagnosis Algorithm Intra-Articular - Bone • Stress
Intra-Articular - Bone ... Osgood-Schlatter Disease ... Ganglion Cyst - Bone ... Intraarticular #MSK ... #Orthopedics #Causes
Osgood-Schlatter Disease - MSK Radiology Imaging Findings: • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... fragmentation and mild ... bone marrow edema ... marrow edema and bony ... Radiology #diagnosis #msk
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis Algorithm ... • Cushing's Disease ... Chemotherapy • Bone ... Celiac, IBD) • ... endocrinology #causes
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... , Biological + Bone ... /ml, ↑ LDH • Bone ... • Autoimmune diseases ... Lymphohistiocytosis #diagnosis #management
Bone Deformity / Limp - Differential Diagnosis Algorithm Infection • Septic Arthritis • Cortical Hypertrophy •
Bone Deformity / ... Differential Diagnosis Algorithm ... Arthritis Other Causes ... • Dwarfism #Bone ... Deformity #Limp #MSK
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