16 results
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
column) • Late complication ... : ankylosed spine ... (bamboo spine) ... AnkylosingSpondylitis #pathophysiology ... #diagnosis #signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Musculoskeletal Manifestations ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... dermal-epidermal junction ... #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Neoplasm in lumbar spine ... etc) in lumbar spine ... Signs / Symptoms ... / Complications ... Syndrome #MSK #pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... impairs musde function ... Spectrum of Clinical Manifestations ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... Pain worse when supine ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... Symptoms related to complications ... inducing vomiting #BulimiaNervosa ... #pathophysiology ... #diagnosis #signs
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
has good renal function ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
without neuro manifestations ... Collapse: • Pathophysiology ... → Syncope • Signs ... dysfunction • Other manifestations ... Loss of muscle function