35 results
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... spontaneously (before any treatments ... leukemia (both ALL ... malignancies Treatments ... #Tumor #Lysis #Syndrome
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... hyperleukocytosis (AML ... Hyperviscosity #Syndrome ... Differential #Diagnosis #Treatment
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... Antiphospholipid antibodies (aPL ... Anticardiolipin antibodies (aCL ... to be present Treatment ... Antiphospholipid #Syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... have fever - ACS ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
fluid analysis in all ... workup • Test all ... Arthritis-Dermatitis syndrome ... Purulent Arthritis Syndrome ... Distal joints, knees
Management of Serotonin Syndrome
Identify and stop all serotoninergic medications
 • Avoid inadvertent Rx of serotoninergic meds
Management of Serotonin Syndrome ... Identify and stop all ... ucsdim #Serotonin #Syndrome ... #Management #treatment
REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV

Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia
99: Serotonin Syndrome ... Cornerstone of treatment ... discontinuing all
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... complete paralysis of all ... Miller Fisher Syndrome ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... factor (GCSF) treatments ... marrow studies Treatment ... progression to AML ... Immunosuppressive treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... Renal Failure Treatment ... Differentiation #Syndrome