1060 results
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Expression → ↑ VLDL ... /Secretion → ↑ LDL ... Production → ↑ LDL ... Receptors → ↑ LDL ... Clearance → ↓ Plasma LDL-C
Abnormal Lipid Profiles - Differential Diagnosis Algorithm

Increased Cholesterol and Triglycerides 
 - Genetic Causes
Hypothyroidism Decreased HDL ... Androgens Increased LDL ... ApoB-100 • LDLr ... • Familial LPL
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Algorithm • 12-13 g/dL ... /uL Initial Workup ... reticulocyte count, LFTs, LDH ... Algorithm #hematology #workup
Luftsichel Sign in Left Upper Lobe Collapse - Chest X-Ray

An upper lobe collapse causes the collapse
Sometimes the LLL ... the collapsed LUL ... the air in the LLL ... Luftsichel #Sign #LUL ... #Chest #XRay #CXR
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Unconjugated bilirubin LDH ... Laboratory #Testing #workup
Chest Pain - Diagnosis and Workup Algorithm

History and Exam
Acute life-threatening causes:
 • Acute myocardial infarction
 •
Diagnosis and Workup ... rupture Initial workup ... ultrasound • CXR ... Diagnosis #Algorithm #workup
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Lysis Syndrome - Workup ... Management Initial workup ... Serum uric acid, LDH ... Uric acid ≥ 8 mg/dL ... Calcium ≤ 7 mg/dL
Differential Diagnosis of Hypoglycemia
Evaluation of Hypoglycemia
Patients with known diabetes who are not systemically ill and can
, no extensive workup ... EtOH - Infectious workup ... : CXR, UA, urine
COVID-19 Biomarkers 
 - Troponin
 - D-dimer
 - Lymphocyte Count
 - IL-6
 - LDH
 - Fibrinogen
Count - IL-6 - LDH ... Laboratory #Testing #Workup
Risk factors for atherosclerosis

Modifiable risk factors:
 - Dyslipidemia (elevated LDL, decreased HDL)
 - Tobacco smoking
 -
Dyslipidemia (elevated LDL ... , decreased HDL)