23 results
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
CRAB #SLIMCRAB #Oncology ... #HemeOnc #Hematology ... Hypercalcemia #Anemia ... #Clinical #Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... Heart Valve) #Thrombocytopenia ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... Thrombotic idiopathic thrombocytopenia ... #differential #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... changes), high MCV anemia ... gastric bypass), LFT ... or if a primary hematologic ... Causes #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... infections/fevers • Thrombocytopenia ... Constitutional Syndromes ... #oncology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... microangiopathy: Thrombotic thrombocytopenic ... Hemolytic uremic syndrome ... differential #diagnosis #hematology ... #anemia
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... 5) Symptoms of anemia ... or thrombocytopenia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH) Clinical ... : ↑↑ ferritin, Anemia ... , Thrombocytopenia ... Lymphohistiocytosis #diagnosis #hematology