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diagnosis hematology clinical differential causes coagulation hepatology pt skin transaminitis ucsdh abnormal aptt cellulitis infection laboratory prolonged rash rheumatology skinrash
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... more specific for hepatic ... #Enzymes #LFTs
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - ... (Drug-induced liver ... ) • Non-hepatic ... Function #Tests #LFTs
Liver Abscess on POCUS 24yo healthy F to ED w/rigors &DCed. 2/2 blood cx + for fusobacterium,
Liver Abscess on ... asymptomatic, CBC/chem/LFTs ... of this 2x2cm liver ... twitter.com/EUSmkh #Liver ... #Abscess #Hepatic
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 Spider Angioma: Dialated superficial arterioles, most commonly associated with advanced liver disease. Charlie Goldberg, M.D. - UCSD
with advanced liver ... Images #Clinical #Photo ... #Dermatology #Rash
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... Interpretation of LFTs ... Identify Acute Liver ... replaced by non-hepatic ... transaminitis #LFTs
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Medications - Heparin ... ) • Advanced Liver ... • Acute DIC - Septic ... comparison #diagnosis #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
inhibitor • Liver ... elevated in: • Heparin ... Thromboplastin #laboratory #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
dysfunction (25%) • Hepatic ... DIC • Severe Liver ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... treatment #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
: INR/PT, aPTT(liver ... gastric bypass), LFT ... (liver disease) ... Causes #Workup #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... unfractionated heparin ... cause e.g. heparin ... Reduced liver synthesis ... #differential #hematology
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