3 results
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
• Inhibit Na+ reabsorption ... loss through the nephron ... inhibiting antidiuretic hormone ... #Pharmacology #nephrology ... loop #thiazide #classes
Pathophysiology - Renal compression as a mechanism of obesity hypertension. 
Compression of the thin loop of
Pathophysiology ... - Renal compression ... increased sodium reabsorption ... individuals prior to nephron ... hypertension #obesity #pathophysiology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
• Incr Bone resorption ... Incr renal [Ca2+] load ... Skull expansion causes ... cranial nerves run, compressing ... PagetsDisease #pathophysiology