14 results
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... vs. 1) • Fewer ACS ... Benefits #SickleCell #pathophysiology ... #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology #
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings
Classification of PCL Iniuries
 • Partial: Translation <
Cruciate Ligament (PCL ... structures, such as the ACL ... Posterior draw test, - Lachman ... Posterior draw test, + Lachman ... #MSK #Sports #pathophysiology
Fibrinolysis. 
Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
and urokinase act ... -antiplasmin), act ... Fibrinolysis #Pathway #Pathophysiology ... #Plasminogen #Pharmacology
Stress Ulcer Prophylaxis

Stress ulcerations are common in ICU patients and may lead to hemorrhage if not
hospitalization) • Pathophysiology ... #Prophylaxis #criticalcare ... #pharmacology #
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Adrenalin - "Epi" - ACLS ... Inotropes #management #criticalcare ... comparison #table #pharmacology
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Can be used in all ... comparison #table #pharmacology ... #criticalcare
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
filtered Na+/K+/Cl ... filtered Na+ and Cl ... Segments #Function #Pathophysiology ... Tubules #Table #Pharmacology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
this post will focus ... its Chloride (Cl ... are balanced by Cl ... #foamed #criticalcare ... diagnosis #treatment #pharmacology