18 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... (late) • High ... Urine Cl-: Diuretics ... Bartter Syndrome, Gitelman ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... (late) • High ... Urine Cl-: Diuretics ... Bartter Syndrome, Gitelman ... Diagnosis #Algorithm #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... distal tubule. ↑ Nacl ... delivery to distal nephron ... → Hypokalemia Metabolic ... Pathophysiology #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
loop or thiazide diuretics ... pressure: Active diuretic ... Bartter syndrome, Gitelman ... acidosis, a high ... urine #Algorithm #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Low intake • Metabolic ... Syndrome • HTN, High ... Loop and thiazide diuretics ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypertensive: • High ... Al, High R - Secondary ... >20 mEq/24 h - Diuretics ... Bartter's syndrome, Gitelman's ... Diagnosis #Algorithm #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... loss through the nephron ... #Pharmacology # ... nephrology #conversion
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... tubular transport • Diuretics ... Hypomagnesemia • Barrter's/Gitelman's ... High Renin, High ... MetabolicAlkalosis #NonGap #Nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... (late) • High ... Urine Cl-: Diuretics ... Bartter Syndrome, Gitelman ... Diagnosis #Algorithm #Nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
mmol creatinine) High ... diuretics, Thiazide ... diuretics, Mg2+ ... Bartter syndrome, Gitelman ... algorithm #diagnosis #nephrology