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differential infections management signs cord disease disorders encephalitis fungal fuo headache infectiousdiseases lyme meningitis mnemonic mycoses myelitis phantoms rheumatology sarcoidosis
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Further Workup • CNS ... symptoms? ... Refer to your ‘Fever ... thin smear • Signs ... node biopsy • Clinical
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
inflammatory cells) Clinical ... Constitutional: Fever ... exertion • Neurologic ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
Algorithm Red ... ) • Systemic symptoms ... , fever, myalgia ... brain lesion • CNS ... #Algorithm #neurology
Lyme Disease: Early and Late Clinical manifestations Stage 1. Localized • EM appears 7-14 days at the
Early and Late Clinical ... arthralgia, headache, fever ... lymphocytic meningitis, CN ... Lyme #Disease #diagnosis ... #signs #symptoms
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Fever, cough ... has five major clinical ... fungal stain of clinical ... especially the CNS ... MC: CNS CSF: •
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... • Headache • Fever ... • Common clinical ... Acute meningeal signs ... (fever, nuchal
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... affects the skin, neurologic ... • Progressive symptoms ... chorioretinitis, CNS
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... and signs below ... dysfunction • Abnormal reflexes ... #neurology #differential ... #algorithm
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... #management #neurology
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