18 results
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
Colchicine Toxicity ... #Colchicine #Toxicity ... #Toxicology #Symptoms ... #Signs #Diagnosis
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
hydroxybutyrate (GHB) - Toxicology ... presentation - Symptoms ... of GHB toxicity ... Hydroxybutyrate #GHB #Toxicology ... #Toxicity #Diagnosis
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... caustic mucosal injury ... post-ingestion) - Symptom ... caustic bowel injury ... #Toxicology #Diagnosis
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
anaerobic metabolism Diagnosis ... and acute kidney injury ... also includes symptoms ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis
Carbon Monoxide Poisoning

Symptoms are non-specific:
 - Headache 90%
 - Nausea/vomiting 50%
 - Vertigo 50%
 - Altered
Monoxide Poisoning Symptoms ... affected (inc pets ... Outdoors improves symptoms ... Monoxide #Poisoning #Toxicology ... #diagnosis #management
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... - Diagnosis and ... ingestion/exposure Symptoms ... Salicylate #Aspirin #Toxicity ... #Toxicology #diagnosis
Reported Mechanisms and Toxicity of Investigational Treatments for SARS-COV-2
Chloroquine and Hydroxychloroquine
 • Mechanisms: Interference with ligand
Mechanisms and Toxicity ... 3 response • Toxicity ... hearing loss, GI symptoms ... acidosis, renal injury ... #Toxicology #Medications
Osteosarcoma 
Most common primary malignant bone tumor in children 
Most Common Sites of Involvement:
1. Distal femur
frequently begins after injury ... • Systemic symptoms ... #Osteosarcoma #Diagnosis ... Features #Oncology #Peds
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... Direct muscle injury ... Risk of muscle injury ... Atorvastatin Diagnosis ... #myopathy #diagnosis
Digoxin Toxicity Presentation - Signs and Symptoms
 • Visual disturbances (halos, color disturbances)
 • Weakness
 •
Digoxin Toxicity ... Presentation - Signs and Symptoms ... EBmedicine #Digoxin #Toxicity ... #toxicology #Signs ... #Symptoms #diagnosis