37 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Lymphocytosis on CBC ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
'second hit' -> ... 'second hit' -> ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis #signs
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... during transient CD4 ... + T-cell count can
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Summary Clinical Signs ... plasma clonal cell ... is also >100 CMC ... Diagnosis #Management #oncology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... is entirely T-Cell ... -> Particular CD4 ... Stevens-Johnson Syndrome ... Allergy #Immunology #pathophysiology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Cr >2 mg/dL or CC ... marrow plasma cell ... diseases, CML, ... plasmacytoma, POEMs syndrome ... diagnosis #hematology #oncology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
auto-reactive B and CD ... CRP Neuronal cell ... surface targeted -> Cell ... RheumaticFever #pathophysiology ... #diagnosis #signs
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... leukemia (both ALL ... Treatments: • IV ... #Tumor #Lysis #Syndrome ... #TLS #oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... Episcleritis Signs ... general feeling of ill ... - CBC may also ... #dermatology #oncology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... should be done in ALL ... intervention CMC