15 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... tubule #Liddle ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... delivery to distal nephron ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Algorithm Extra-renal ... loss (Diarrhea) Renal ... Low Aldosterone: Liddle's ... , Gitelman syndrom ... potassium #low #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
, Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... GRA, Cushing's syndrome ... , Liddle syndrome ... Diagnosis #Algorithm #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... in cardiorenal syndrome ... • Increased renal ... #Mechanisms #pathophysiology ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
, Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... GRA, Cushing's syndrome ... , Liddle syndrome ... Diagnosis #Algorithm #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... ascending limb Gitelman ... convoluted tubule Liddle ... receptor Distal renal ... Defects #Kidney #Nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
gastrointestinal K loss • Renal ... hypokalemia • Renal ... , Gitelman's syndrome ... glycyrrhizic acid, Liddle's ... algorithm #causes #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Chloridorrhea Renal ... Hypomagnesemia • Barrter's/Gitelman's ... • Licorice • Liddle's ... Syndrome • Enzyme ... MetabolicAlkalosis #NonGap #Nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
suggests extra-renal ... mineralocorticoid excess, Liddle's ... syndrome, Congenital ... , Gitelman syndrome ... differential #potassium #nephrology