8 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... and Pregnancy ... @Bloodman #Thrombocytopenia ... AFLP #Obstetrics #OBGyn ... #Hematology #Diagnosis
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
results of HIT laboratory ... Diagnosis #Management #Hematology ... #HIT #Heparin #Induced ... #Thrombocytopenia
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... #Fatty #Liver #Pregnancy ... #hepatology #obstetrics ... #obgyn #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
thrombin time • Reduced ... , V and II • Reduced ... protein C and S Pathophysiology ... venipuncture sites Laboratory ... treatment #management #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... Thrombocytopenia ... ♀, ↑Age, ESRD Pathophysiology ... #HIT #Heparin #Induced ... Management #Treatment #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Intravenous Drug Use • Pregnancy ... Hyperhomocysteinemia - Heparin-induced ... thrombocytopenia ... Venous #Arterial #pathophysiology ... #hematology #differential
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
synthesis, not reduced ... Chemistry #Tests #Laboratory ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... cholestasis of pregnancy ... Sarcoidosis, Drug-induced ... diagnosis #workup #hepatology