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hematology management doac anticoagulation algorithm cancer diagnosis malignancy vte anticoagulant apml carcinoma cascade causes chemotherapy coagulation cyp3a4 dic differentiation disseminated
Coagulation Cascade and Anticoagulant Sites of Action - Amy Chung, MD, MSc https://twitter.com/AmyChung #AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade and Anticoagulant ... AntiCoagulation #Cascade #Anticoagulants ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... direct-acting oral anticoagulants ... direct-acting oral anticoagulant ... Anticoagulation #Management #Hematology ... #Oncology
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 Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
consider withholding anticoagulant ... decision to continue anticoagulant ... DOAC, direct oral anticoagulant ... Anticoagulation #Management #Hematology ... #Oncology
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
procedure Stop anticoagulant ... treatment; volume ... Reversal #NOAC #Oral #anticoagulant ... #hematology #management ... #pharmacology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... diagnosis #management #hematology ... #oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Reduction of pro/anticoagulants ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline First Line Treatment for HCC with Preserved
First Line Treatment ... Function Second Line Treatment ... #Management #Hepatology ... Gastroenterology #oncology ... #Pharmacology
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