11 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade and Anticoagulant ... AntiCoagulation #Cascade #Anticoagulants ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
Direct-acting oral anticoagulants ... (DOACs) for VTE ... treatment and prevention ... Anticoagulation #VTE ... #Management #Pharmacology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... and bridging for VTE ... Clotmaster #VTE ... #Loading #DVT #Pharmacology ... #Hematology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
and Novel Oral Anticoagulants ... - Pathophysiology ... the mainstay of VTE ... or a new oral anticoagulant ... #Pharmacology #Pathophysiology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... direct-acting oral anticoagulants ... direct-acting oral anticoagulant ... body mass index; VTE ... #DOAC #VTE #Malignancy
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
for VTE in Malignancy ... consider withholding anticoagulant ... risk of recurrent VTE ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
Choice of anticoagulant ... for treatment of ... Pregnancy - LMWH #anticoagulant ... #decisionaid #vte ... anticoagulation #pharmacology
Warfarin - INR Goals, Initial Dosing and Bridging

Mechanical Mitral Valve Replacement 2.5-3.5 
Other Valve Replacement 2-3
Replacement 2-3 VTE ... Treatment/Prophylaxis ... VTE treatment), ... depletion of natural anticoagulants ... Bridging #Initiation #Pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
procedure Stop anticoagulant ... treatment; volume ... Reversal #NOAC #Oral #anticoagulant ... #hematology #management ... #pharmacology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Reduction of pro/anticoagulants ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology