12 results
Coombs Test - Direct vs Indirect

#Diagnosis #Testing #Coombs #Direct #Indirect #Hemolytic #Anemia
Coombs Test - Direct ... #Diagnosis #Testing ... #Coombs #Direct ... #Indirect #Hemolytic ... #Anemia
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
Disease - Laboratory ... Testing SUMMARY ... non-invasive test ... #Chronic #Disease ... #Laboratory #Testing
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
NEUROLOGIC - HEMOLYTIC ... ANEMIA - LEUKOPENIA ... CH50) - Direct Coombs ... ’ test (in the absence ... of hemolytic anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
dehydrogenase • Positive Coombs ... testing for anti-C3d ... • Diagnostic Test ... Donath-Landsteiner test ... #hemolytic #anemia
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Iron Deficiency Anemia ... patients with anemia ... • Additional laboratory ... disease with serology ... Non-invasive testing
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... , Drugs, Liver Disease ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... value is low, tests ... result in severe anemia ... anemia Indirect
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Studies in Rheumatic Diseases ... - CCP antibody testing ... the presence of anemia ... more time for the laboratory ... Rheumatoid #Arthritis #laboratory
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
e.g., indirect Coombs ... test) Crossmatch ... - involves testing ... false negatives on testing ... Borrellia (Lyme disease
Diagnostic Scoring System for Wilson's Disease
 - Kayser-Fleischer rings (2 points)
 - Neurological symptoms (2 points)
System for Wilson's Disease ... (2 points) - Coombs-negative ... hemolytic anemia ... possible; more tests ... unlikely #Wilsons #Disease