890 results
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic Acidosis ... - Overview and Pathophysiology ... Lactic acid is ... Lactic acid is non-toxic ... differential #diagnosis #pathophysiology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Lactulose → ↑ Lactic ... Acid, Acetic Acid ... ammonia #hepatology #pathophysiology
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
into ketones and lactic ... -> Ketones and lactic ... Hyperuricemia #Pathophysiology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Metformin Associated Lactic ... Acidosis (MALA) Pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
organic acids like lactic ... Hyperuricemia #Pathophysiology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... directly and via lactic ... Pressure #ICP #Pathophysiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
also seen • Lactic ... beriberi #nutrition #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... Possible DIC - Mild lactic
Bone resorption and the relationship between osteoblasts and osteoclasts.  
RANK is expressed on the osteoclasts,
. citric acid, lactic ... #Pathophysiology
Metabolic Pathways of Toxic Alcohols 

Panel A shows the metabolic pathways of toxic alcohols. Alcohol dehydrogenase
propylene glycol to D-lactic ... and L-lactic acid ... #Pathophysiology