10 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Proximal tubule Bartter ... Thick ascending loop ... Syndrome #Fanconi #Bartter ... #Localization #Nephron ... #Defects #Pathophysiology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... on the Kidney - Pathophysiology ... modify immune function ... reabsorption in Proximal, loop ... #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... limb of Henle's loop ... (TAL) - Active ... #Pathophysiology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... Remote use of loop ... Vomiting/nasogastric suction ... diuretic use, Bartter ... mineralocorticoid-like effect
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Physiological Effects ... Altered Renal Function ... excretion in distal nephron ... AngiotensinII #Pathophysiology ... #Action
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Ileostomy - NGT suction ... - Diuresis - Bartter ... transport, renal function ... #Pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... Remote use of loop ... Vomiting/nasogastric suction ... diuretic use, Bartter ... mineralocorticoid-like effect
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... Non-reabsorbable anion ... effect: Vomiting ... High Urine Cl - Loop ... Mg2+ deficiency, Bartter
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
vomiting/ nasogastric suction ... • Thiazide or loop ... tubule diuretic effect ... • Thiazide or loop ... actively working • Bartter
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Differential Diagnosis Algorithm ... Vomiting • NG suction ... contracted • Loop ... diuretics / Bartter's ... Differential #Diagnosis #Algorithm