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hematology oncology syndrome blood clinical product reactions treatment anemia aplastic canimorsus capnocytophaga coagulation dic differential disseminated dress gangrenosum injury intravascular
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Acute Kidney Injury ... Glomerular (red blood cells ... Interstitial (eosinophils ... appropriate) #Acute ... Kidney #Injury #AKI
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Criteria for Diagnosis ... • SJS/TEN • Acute ... DRESS #Syndrome #dermatology ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... = funny-shaped cells ... old, ~10,000 new cases ... transformation to acute ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... , acute limb ischemia ... Syndrome #TLS #diagnosis ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... -> AML: Blast crises ... • (Peripheral eosinophilia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Hepatitis, eosinophilic ... number of CD34+ cells ... Anemia #oncology #hematology ... #diagnosis #management
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... selsis after a ... the key to the diagnosis ... Canimorsus #Skin #Rash #dermatology ... #clinical #photo
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... Transfusion Related Acute ... potassium from lysed cells ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Related Acute ... potassium from lysed cells ... #Transfusions #diagnosis ... #management #hematology
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