28 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... , dyspnea, +/- CXR ... Lysis of tumor cells ... Syndrome #TLS #diagnosis ... #management #hematology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... necrosis (7-14 days later ... Blood cultures • CXR ... early disease) • CXR ... #management #treatment
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
indicated, start CPR ... thoracotomy is a better treatment ... Plan definitive management ... Intraoperative #Checklist ... #Diagnosis #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... common • Imaging: CXR ... Renal Failure Treatment ... #management #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral ... - Causes progressive ... Escorial criteria uses ... column Treatment ... #management
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... AP, ↑INR, ↑BUN/Cr ... ) Differential Diagnosis ... Liver #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
and Management ... Treatment: • Global ... Rifaximin- up to 3 courses ... intestinal epithelial cells ... #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Drugs, Unknown cause ... Treatment: • ... #management #treatment ... #summary #rheumatology
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... arrest, start CPR ... require prolonged treatment ... Intraoperative #Checklist ... #Diagnosis #Management