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diagnosis treatment hemophagocytic hlh lymphohistiocytosis syndrome acquired anemia antibody cd4 classification diseases hemeonc hemolytic hodgkins icl idiopathic lymphocytopenia lymphoma lymphopenia
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... • Blood smear: Differential ... 2) LOOK FOR a cause ... Anemia #diagnosis #management ... #treatment #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... thrombocythemia), Autoimmune ... adsorption onto cancer cells ... #treatment #hematology ... #differential
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... solid cancers • Autoimmune ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Multinucleated giant cells ... tract, and often causes ... #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Immunosuppression • Autoimmune ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Subglottic stenoses (SGS) during systemic diseases Subglottic stenosis (SGS) = congenital (children) or acquired (adult) characterized by
• Immunology : ANCA ... Laryngotracheal cancer • Autoimmune ... systemic #diseases #differential ... #diagnosis #causes ... #rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
T-cell count of 300 cells ... W/ LOW CD4 • Autoimmune ... ICL #diagnosis #hematology ... #Differential # ... Causes #lymphocytopenia
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... RP-ILD), dermato-rheumatologic ... statins - probably caused ... Myositis #Myopathy #rheumatology ... #differential #
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
overgrowth of cells ... mesothelioma, etc - Autoimmune ... Sjögren’s syndrome, ANCA-associated ... TAFRO #diagnosis #management ... #rheumatology #
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