41 results
diagnosis management hematology oncology syndrome differential ocular persistent physicalexam ppm pupillary signs video hemeonc neurology symptoms workup algorithm anemia chronic
Sickle Cell Disease - Pathophysiology of disease and complications Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... HbS induces RBC membrane ... crosslinking of the membrane ... the sickle red cells ... Complications #Hematology
Persistent Pupillary Membrane (PPM) on Slit Lamp Ocular Examination This membrane would be a remainder of the
Persistent Pupillary Membrane ... tunica vasculosa lentis ... large enough to cause ... #PhysicalExam #clinical ... #video #ophthalmology
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 Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
adsorption onto cancer cells ... Extracorporeal membrane ... Diagnosis #Management #treatment ... #hematology #differential
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... epithelial basement membrane ... epidermis from dermis Clinical ... - Erosions and crusts ... Diagnosis #Management #dermatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... for secondary causes ... eosinophilia (common causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
(LP) tumour B cells ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
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