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Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Hyperviscosity Syndrome ... of breath • Neurologic ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... old, ~10,000 new cases ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
BEE Syndromes - ... recessive—Usher syndrome ... MS • Other • Syndromes ... aura #BEE #Syndromes ... #differential #
Localizing Extraocular Movement Disorders
 • CN Ill (Oculomotor) Nerve Palsy 
 • CN IV (Trochlear) Nerve
One-and-a-half Syndrome ... Skew Deviation Casey ... #Localization #ophthalmology ... #neurology #differential
Important Causes of Diplopia 
TIER 1-CRITICAL
Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn
TIER 2-EMERGENT:
Vertebral dissection, Myasthenia gravis,
Important Causes ... , Orbital apex syndrome ... Miller-Fisher syndrome ... mass #Diplopia #differential ... #diagnosis #ophthalmology
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Hypophosphatemia - Differential ... Redistribution/ Shift into cells ... ), Hungry bone syndrome ... Diagnosis #Algorithm #causes ... #nephrology #phosphate
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
osmolarity If cause ... investigations depending on clinical ... Abdominal compartment syndrome ... • Cardio-renal syndrome ... #causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... (CML) • Felty Syndrome ... blood count with differential ... diagnosis #hematology #oncology
Priapism 

Secondary Causes:
Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine
Any hyperviscosity syndrome (SCD, leukemia,
Secondary Causes ... hyperviscosity syndrome ... Priapism #Diagnosis #Management ... #Urology #Differential
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Hypertension - Differential ... based on repeat clinic ... • Nephritic syndrome ... Excess: • Conn's syndrome ... Licorice • Liddle's syndrome