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differential management oncology hemeonc syndrome anemia apml causes chronic classification cll differentiation disorders emergencies eosinophil eosinophilia fuo hemolytic hemophagocytic heon
Pediatric Neutropenia Workup Algorithm DOI: 10.1111/ijlh.13210 #Neutropenia #Workup #Algorithm #diagnosis #hematology #Pediatrics #peds
Algorithm DOI: ... #Neutropenia #Workup ... #Algorithm #diagnosis ... #hematology #Pediatrics ... #peds
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... Returning Traveler’ algorithm ... thin smear • Signs ... values supporting hematologic ... #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Algorithm • Sickle ... cells - Consider ... bartonella (oroya fever ... #Algorithm #workup ... #hematology #testing
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... #workup #oncology ... #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... Too many cells in ... Better call hematology ... #Algorithm #workup ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Release from blast cells ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... opacities • Diagnosis ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... Lysis of tumor cells ... Syndrome #TLS #diagnosis ... #management #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
BM biopsy (Mast cells ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology ... #Workup
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... classification #hematology
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