20 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... • Ex: Systemic Lupus ... Immunological Mediator: Th Cells ... #Types #Classification ... #Diagnosis #Definitions
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... causes are asthma, allergy ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... , and systemic lupus ... Hypersensitivity #Types #Classification ... #Diagnosis #Reactions
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... • Systemic Lupus ... • Acne • Allergy ... Reed-Sternberg Cells ... Algorithm #Causes #Hematology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... glomerulonephritis, Systemic lupus ... reactions #types #allergy ... #table #classification ... #comparison
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential Diagnosis ... #Classification ... pathophysiology #Hematology ... #Diagnosis #NonHodgkin
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Differential Diagnosis ... Malignancy (e.g. hematologic ... ) • Endocrine disorders ... Erythematosus #Diagnosis
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... similarly to mast cells ... released during an allergic ... Myeloproliferative Disorders ... #causes #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... symptoms, unexplained hematologic ... EBV viral load, signs ... and classification ... #oncology #diagnosis
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
- Differential Diagnosis ... Disease: Discoid lupus ... Scarring Alopecia: Lupus ... Examination: • Signs ... #Differential #Diagnosis