121 results
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
required for dx - T-cells ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... are NK cells (sCD3 ... hemepath #pathology #diagnosis
Autoimmune Gastritis - Pathophysiology

Anti-ParietaI Cell, CD4+ T Cells, Autoantibodies -> x Parietal Cells, x HCL, x
Autoimmune Gastritis - Pathophysiology ... Anti-ParietaI Cell, CD4 ... + T Cells, Autoantibodies ... -> x Parietal Cells ... Autoimmune #Gastritis #Pathophysiology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... - T-cell - CD7 ... , CD3 Chronic ... or λ), Smudge Cells ... #Differential #Diagnosis
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
mononuclear phagocytic cells ... and infect other cells ... Leishmaniasis #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
dendritic cell (DC ... activate naive CD4 ... T cells. ... These T cells then ... #asthma #pathophysiology
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Activated T cells ... responses, and B cells ... associated with CD4 ... or CD8, depending ... ImmuneResponses #immunology #pathophysiology
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
CD3-CD4+ T cells ... #Differential #Diagnosis
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
- Differential Diagnosis ... Transcellular Shift Into Cells ... imports K+ into cells ... #Differential #Diagnosis ... potassium #low #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
-> Particular CD4 ... + Th cells recognize ... harmful -> Th Cells ... macrophages, mast cells ... Allergy #Immunology #pathophysiology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Pathophysiology: ... germinative skin cells ... Skin-homing T-cells ... #Diagnosis #