15 results
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
- incr H+ (acidosis ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential ... #Causes #Diagnosis
Renal Replacement Therapy (RRT) - ICU One Pager Summary
Indications (AIEOU):
 • A: Acidosis (usually severe metabolic)
(AIEOU): • A: Acidosis ... Overload (pulmonary edema ... Dialyzer is rigid case ... HD machine • CRRT ... #managment #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... smooth muscle cells ... metabolic acidosis ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... e.g., uptake by cells ... Acute pulmonary edema ... 30mmHg) - Severe anemia ... #Elevation #Differential
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
including laxative, enema ... Renal tubular acidosis ... megaloblastic anemia ... #differential # ... diagnosis #nephrology
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Renal: metabolic acidosis ... of thigh/flank edema ... over-diuresis, dialysis/CRRT ... #criticalcare #differential ... #causes #classification
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Renal: metabolic acidosis ... of thigh/flank edema ... over-diuresis, dialysis/CRRT ... #criticalcare #differential ... #causes #classification
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Diagnosis and Management ... only if no clear cause ... Drives K+ into cells ... caution in HTN & edema ... Treatment #potassium #nephrology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... myalgias, HoTN, edema ... initiation • Differential ... coagulopathy, RRT ... APML #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Reversible course Differential ... the underlying cause ... Syndrome #diagnosis #management ... #neurology