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diagnosis hematology neurology syndrome mds myelodysplastic acromegaly als amyotrophic apml bells classification coagulation dic differentiation disseminated dysphagia encephalopathy endocrinology gastroenterology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... transformation to acute ... #treatment #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
GrepMed Handbook Acute ... Diagnosis and Workup ... No additional workup ... CNS inflammatory cause ... #Treatment #Neurology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... - ACS, AKI, acute ... Lysis of tumor cells ... TLS #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Out Secondary Causes ... Workup: • Complete ... blood count with differential ... diagnosis #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... protein C and S Pathophysiology ... + Bleeding Treatment ... Treat primary cause ... #treatment #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Differential Diagnosis ... Diagnosis and Workup ... or refractory cases ... Endocrinology #Treatment ... #Pathophysiology
Dysphagia - Differential Diagnosis Framework Symptom | Diagnosis • Solid-food dysphagia present for months to years | Mechanical
Dysphagia - Differential ... weight loss or acute ... disorder → EGD Treatment ... the underlying cause ... #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Reversible course Differential ... the underlying cause ... • Treatment of ... Syndrome #diagnosis #management
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