17 results
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Malignancies 3. ... HLH syndrome 5. ... Acquired Aplastic Anemia
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Malignancies 3. ... HLH syndrome 5 ... Acquired Aplastic Anemia
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Pre-eclampsia 2) ... Autoimmune: Warm AIHA, Cold ... Drug-associated, PCH, Evans Syndrome ... Disease, PNH 3) ... Defects: Sickle cell anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Disease 3 Types ... (CAD) 2. ... Antibodies[PCH] 3. ... Agglutinin Syndrome ... younger pts) Differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
• M = F • 3 peaks ... : 1) Childhood 2) ... 15-25 years 3) ... Reticulocyte index < 2 ... #oncology #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... (2-48% depending ... Moderate > 2/3 and ... initiation • Differential
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
to work through ... approach to the differential ... 2) Is ADH elevated ... demyelination syndrome ... #Differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... progression to AML ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... Agranulocytosis 3. ... • Richter’s Syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Hyperuricemia • Hyponatremia ... obstruction 3. ... kidney tubular cells ... output: 200 ml/hr 3.