30 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
) Clinical: ... • Disease fatal ... exertion • Neurologic ... neuropathies • Skin ... Diagnosis #Symptoms #Signs
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... #differential # ... diagnosis #dermatology ... #oncology #clinical ... #skin
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... syndrome (SSS) ... , the differential ... includes Kawasaki disease ... #Diagnosis #Dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... reticularis Differential ... • Goodpasture syndrome ... vasculitis #Dermatologic
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... other autoimmune diseases ... Xeroderma (Dry skin ... #Pathophysiology ... #Diagnosis #Signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... injury) • Neurologic ... (Clinical Dx). ... ) Differential Diagnosis ... diagnosis #management #signs
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential ... of inflammatory cells ... SAPHO syndrome ( ... Sweet syndrome ... #Diagnosis #Dermatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Diagnosis Neurologic-Centered ... capillary leak syndrome ... Ig deposition disease ... #Diagnosis #hematology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Approach to the differential ... hemolytic-uremic syndrome ... .2>5 red blood cells ... nose (epistaxis), skin ... #nephrology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... et diutinum Neurologic ... thrombosis+Pulm HTN+skin ... #Monoclonal #Differential