35 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Cytokines, Mast Cells ... perivascular inflammatory cells ... Vasculitis #HUV #Pathophysiology ... #Rheumatology
Bell's Phenomenon on Physical Exam

Carles Bell realized that when trying to close the eye on the
Bell's Phenomenon ... neurologiabr #Bells ... Sign #clinical #video ... #PhysicalExam #ophthalmology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... germinative skin cells ... Skin-homing T-cells ... #Diagnosis #Dermatology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... the sickle red cells ... SickleCell #Disease #Pathophysiology ... Complications #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... Classification #pathophysiology ... #Hematology #Diagnosis
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Diagnosis Framework Hematologic ... leukemia (plasma cells ... Differential #Diagnosis #Pathophysiology
Persistent Pupillary Membrane (PPM) on Slit Lamp Ocular Examination

This membrane would be a remainder of the
tunica vasculosa lentis ... PhysicalExam #clinical #video ... #ophthalmology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma #pathophysiology ... #ophthalmology
Iridodonesis

Physical examination revealed iridodonesis, or “dancing” of the iris, which was elicited by rapid movement of
sign of ectopia lentis ... #PhysicalExam #Video ... #Ophthalmology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
anti-coagulation • Hematologic ... Retina • Ganglion cells ... Occlusion #CRAO #pathophysiology ... #ophthalmology