69 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
nose chondritis, skin ... vasculitis • Hematologic ... criteria for 1) hematologic ... hematopoietic stem cells ... blood myeloid cells
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
rubbing of the skin ... Stevens-Johnson Syndrome ... syndrome, caused ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam #
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Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
of germinative skin ... cells. ... Causes: 1) Exfoliative ... Basophils/Histamine 4) Skin-homing ... #Dermatology #Rash
Genital Skin Ulcers - Differential Diagnosis Algorithm
Painful:
 • Herpes simplex
 • Haemophilus ducreyi (chancroid)
 • Behcet's
Genital Skin Ulcers ... ) • Behcet's syndrome ... ulcerative #skinrash #dermatology ... Diagnosis #Algorithm #causes
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Bone/Joint Causes ... thrombophlebitis Skin ... Brittle nails - Skin ... ulcers - Shiny skin ... extremity #msk #physicalexam
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Systemic and Primary Causes ... == Primary Skin ... Myelodisplastic syndrome ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... for secondary causes ... eosinophilia (common causes ... symptoms (eg, skin ... Differential #diagnosis #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... ) is a skin condition ... Causes: - Idiopathic ... , breast CA - Hematologic ... #diagnosis #dermatology
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
of hair, eyes, skin ... McCune Albright syndrome ... Hyperpigmentation #disorders #skin ... #dermatology #Differential ... Diagnosis #Algorithm #causes