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diagnosis differential management syndrome algorithm causes clinical dermatology leukemia anemia chronic cll hepatology hodgkins lymphocytic lymphoma mds photo rheumatology treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... = funny-shaped cells ... BrighamChiefs #Myelodysplastic ... Management #treatment #hematology ... #oncology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
associated with myelodysplastic ... manifestations #myelodysplastic ... differential #diagnosis #dermatology ... #oncology #clinical
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic ... Myelodysplastic ... #Myelodysplastic ... Syndromes #diagnosis #hematology ... #oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... multiple myeloma, myelodysplastic ... criteria for 1) hematologic ... multiple myeloma or myelodysplastic ... blood myeloid cells
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Liver diseases, Myelodysplastic ... transfusion • Target cells ... anemia • Sickle cells ... alcoholism • Burr cells ... #differential #hematology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Oncologic Emergencies ... Diagnosis Framework HEMATOLOGIC ... ONCOLOGIC EMERGENCIES ... neutrophil count < 500 cells ... STRUCTURAL ONCOLOGIC
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Disorders - Myelodysplastic ... or λ), Smudge Cells ... Blood #Disorders #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Dysplastic • Myelodysplastic ... Macrocytosis, Target Cells ... Algorithm #Causes #Hematology
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
ANC <500 x 10^9 cells ... Diagnosis #criteria #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
• Hypocellular myelodysplastic ... number of CD34+ cells ... number of CD34+ cells ... Aplastic #Anemia #oncology ... #hematology #diagnosis
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