10 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Analysis Hypochromia ... Peripheral #Blood #Smear ... #Analysis #hematology ... #microscopy #interpretation
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... develop leukostasis syndrome ... • Peripheral smear ... • Tumor lysis syndrome ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Peripheral smear ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... transformation to acute leukemia ... Management #treatment #hematology ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... • Hairy Cell Leukemia ... appear normal, but analysis ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... • Peripheral smear ... lymphocytes, smudge cells ... #oncology #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
, breast CA - Hematologic ... certain types of leukemia ... - Lupus - Leukemia ... : - Biopsy - Microscopic ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... ): - Hematologic ... Usually myeloid leukemias ... “big & sticky” cells ... denosumab, steroids, dialysis