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diagnosis differential causes management algorithm anemia leukemia systemic cll generalized hemeonc lymphocytic mds myelodysplastic pruritus workup agglutinin allergy aplastic apml
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Differential Diagnosis Secondary ... hemorrhage) • Chronic ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology ... #secondary
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Age > 50 • Chronic ... Reed-Sternberg Cells ... Algorithm #Causes #Hematology ... #Oncology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Hypersplenism • Secondary ... RA, SLE, PRV, Chronic ... RBCs - Sickle Cells ... , Target Cells ... Algorithm #Causes #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... discoloration) • Chronic ... • Nephrotic syndrome ... NailDisorders #Systemic #Secondary ... #dermatology #Differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Richter’s Syndrome ... leukemia #CLL #Chronic ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
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