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hematology leukemia chronic cll hemeonc lymphocytic myelodysplastic algorithm aplastic differential hemophagocytic hlh lymphohistiocytosis myelodysplasia platelets sjogrens syndromes thrombocytosis treatment workup
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... = funny-shaped cells ... cytopenias (usually anemia ... #MDS #Diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
(MDS) (normal or ... Hypocellular/Hypoplastic MDS ... ) Labs: • Peripheral ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... Smear: • Dysplastic ... blood smear • ... #diagnosis #hematology ... #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Algorithm Peripheral ... Smear concerning ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome ... Matthew Ho, MD
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
: • Peripheral ... smear → small rnature-appearing ... Lauren Banaszak, MD ... Lymphocytic #Leukemia #oncology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... - infiltrates (anemia ... smear: Blasts ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cytometry • Peripheral ... smear: Smudge cells ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... RTA, TYPE I RTA Diagnosis ... Pulmonary amyloidosis, PAH ... #Rheumatology # ... Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... (often termed MAS-HLH ... - Cytopenias (anemia ... #Management #Hematology
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