30 results
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... formed or don’t work ... platelets) • MDS ... Workup: • Complete ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Myelodysplastic syndrome ... • Sickle cells ... Hemolytic uremic syndrome ... #differential #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
(MDS) (normal or ... Hypocellular/Hypoplastic MDS ... result from low blood ... #oncology #hematology ... #diagnosis #management
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Abnormalities: macrocytic anemia ... (MDS) Most met ... (MDS) and/or ... including peripheral blood ... Autoinflammatory #Somatic #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... cytopenias (usually anemia ... #MDS #Diagnosis ... #hematology #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... hematologic: Acute blood ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome ... Matthew Ho, MD
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5. ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Pancytopenia #Workup
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5 ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Pancytopenia #Workup
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal Blood ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... Algorithm #Causes #Hematology
Posterior Reversible Encephalopathy Syndrome (PRES) - Treatment
Blood pressure control:
 • Aim for 10-25% BP reduction within
Encephalopathy Syndrome ... PRES) - Treatment Blood ... titratable IV meds ... potentially causative meds ... #Treatment #Management