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diagnosis treatment differential hematology neurology signs symptoms algorithm rheumatology causes gastroenterology tls lysis tumor bowel cancer dermatology disease ibs irritable
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... transformation to acute leukemia ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Rapidly rising blast cells ... : Granulocytic cells ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Antifungal Agents Frequently Used in Leukemia Antibiogram: • Fluconazole • Itraconazole • Voriconazole • Posaconazole • Caspofungin
Frequently Used in Leukemia ... #Antifungal #Leukemia ... #pharmacology #management ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Skin: - CLL cells ... or basket cells ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Neoplastic: - Leukemia ... Lymphoblastic Leukemia ... Chronic Lymphocytic Leukemia ... Reed-Sternberg Cells ... Causes #Hematology #Oncology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic M - Malignancy: Leukemia cutis,
the Rash in a an oncology ... - Malignancy: Leukemia ... Dermatoses: Sweet Syndrome ... #skin #Rash #oncology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Oncologic Emergencies ... Hyperviscosity Syndrome ... neutrophil count < 500 cells ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome ... Plasmapheresis - Leukemia ... Hydroxyurea - Leukemia ... Hyperviscosity #Syndrome ... Diagnosis #Treatment #Management
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation
Lymphoblastic Leukemia ... Lymphoblastic #Leukemia ... Treatment #timeline #oncology ... pediatrics #peds #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... hematology #diagnosis #management
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